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Deregulation of the miR-16-KRAS axis promotes colorectal cancer

KRAS plays a significant role in the etiology and progression of colorectal cancer (CRC), but the mechanism underlying this process has not been fully elucidated. In this study, we found that the KRAS protein levels were higher in CRC tissues than in the normal adjacent tissues, whereas its mRNA lev...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: You, Chaoying, Liang, Hongwei, Sun, Wu, Li, Jialu, Liu, Yanqing, Fan, Qian, Zhang, Haiyang, Yue, Xin, Li, Jing, Chen, Xi, Ba, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114589/
https://ncbi.nlm.nih.gov/pubmed/27857191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37459
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