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Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes

Aromatic cation activation is a useful strategy to promote deoxyfunctionalization; however, the deoxyfluorination of alcohols with cyclopropenium cation remains an unsolved problem due to the weak nucleophilicity of fluoride ion. Here we report the use of 3,3-difluoro-1,2-diarylcyclopropenes (CpFluo...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Li, Lingchun, Ni, Chuanfa, Wang, Fei, Hu, Jinbo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114535/
https://ncbi.nlm.nih.gov/pubmed/27841256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13320
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