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Deoxygenative gem-difluoroolefination of carbonyl compounds with (chlorodifluoromethyl)trimethylsilane and triphenylphosphine

Background: 1,1-Difluoroalkenes cannot only be used as valuable precursors for organic synthesis, but also act as bioisosteres for enzyme inhibitors. Among various methods for their preparation, the carbonyl olefination with difluoromethylene phosphonium ylide represents one of the most straightforw...

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Detalhes bibliográficos
Main Authors: Wang, Fei, Li, Lingchun, Ni, Chuanfa, Hu, Jinbo
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943835/
https://ncbi.nlm.nih.gov/pubmed/24605155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.32
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