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Enantioselective nucleophilic difluoromethylation of aromatic aldehydes with Me(3)SiCF(2)SO(2)Ph and PhSO(2)CF(2)H reagents catalyzed by chiral quaternary ammonium salts

BACKGROUND: Although the nucleophilic difluoromethylation of aldehydes, ketones, and imines has been realized with PhSO(2)CF(2)H and related reagents, there are still no reports on the enantioselective nucleophilic reactions. RESULTS: With a chiral quaternary ammonium salt as the catalyst and KOH as...

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מידע ביבליוגרפי
Main Authors: Ni, Chuanfa, Wang, Fang, Hu, Jinbo
פורמט: Artigo
שפה:Inglês
יצא לאור: Beilstein-Institut 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486490/
https://ncbi.nlm.nih.gov/pubmed/18941491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.4.21
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