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Catalytic Enantioselective Nucleophilic Addition of Ynamides to Aldehydes
The first catalytic asymmetric addition of ynamides to aliphatic and aromatic aldehydes is described. This reaction provides unprecedented access to a diverse family of N-substituted propargylic alcohols that are obtained in high yield and ee in the presence of 10 mol% of zinc triflate and N-methyle...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977694/ https://ncbi.nlm.nih.gov/pubmed/24519669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc00394b |
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