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Catalytic Enantioselective Nucleophilic Addition of Ynamides to Aldehydes

The first catalytic asymmetric addition of ynamides to aliphatic and aromatic aldehydes is described. This reaction provides unprecedented access to a diverse family of N-substituted propargylic alcohols that are obtained in high yield and ee in the presence of 10 mol% of zinc triflate and N-methyle...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cook, Andrea M., Wolf, Christian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977694/
https://ncbi.nlm.nih.gov/pubmed/24519669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc00394b
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