Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression.

The p53 gene is a frequent target of mutation in a wide variety of human cancers. Previously, it was reported that conditional expression of wild-type p53 protein in a cell line (GM47.23) derived from a human glioblastoma multiform tumor had a negative effect on cell proliferation. We have now inves...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Mercer, W E, Shields, M T, Lin, D, Appella, E, Ullrich, S J
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1991
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1958
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