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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

To investigate the effect that human wild-type p53 (wt-p53) expression has on cell proliferation we constructed a recombinant plasmid, pM47, in which wt-p53 cDNA is under transcriptional control of the hormone-inducible mouse mammary tumor virus promoter linked to the dominant biochemical selection...

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Detalhes bibliográficos
Main Authors: Mercer, W E, Shields, M T, Amin, M, Sauve, G J, Appella, E, Romano, J W, Ullrich, S J
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54493/
https://ncbi.nlm.nih.gov/pubmed/2143581
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