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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

To investigate the effect that human wild-type p53 (wt-p53) expression has on cell proliferation we constructed a recombinant plasmid, pM47, in which wt-p53 cDNA is under transcriptional control of the hormone-inducible mouse mammary tumor virus promoter linked to the dominant biochemical selection...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mercer, W E, Shields, M T, Amin, M, Sauve, G J, Appella, E, Romano, J W, Ullrich, S J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6166
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