Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure

We previously reported that endoplasmic reticulum (ER) stress is induced in the subfornical organ (SFO) and the hypothalamic paraventricular nucleus (PVN) of heart failure (HF) rats and is reduced by inhibition of mitogen-activated protein kinase (MAPK) signaling. The present study further examined...

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Bibliographic Details
Published in:Am J Physiol Heart Circ Physiol
Main Authors: Wei, Shun-Guang, Yu, Yang, Weiss, Robert M., Felder, Robert B.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
Subjects:
Cardiovascular Neurohormonal Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114465/
https://ncbi.nlm.nih.gov/pubmed/27496879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00362.2016
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