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ERK1/2 MAPK signaling in hypothalamic paraventricular nucleus contributes to sympathetic excitation in rats with heart failure after myocardial infarction

Brain MAPK signaling pathways are activated in heart failure (HF) induced by myocardial infarction and contribute to augmented sympathetic nerve activity. We tested whether decreasing ERK1/2 (also known as p44/42 MAPK) signaling in the hypothalamic paraventricular nucleus (PVN), a forebrain source o...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Yu, Yang, Wei, Shun-Guang, Zhang, Zhi-Hua, Weiss, Robert M., Felder, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865063/
https://ncbi.nlm.nih.gov/pubmed/26801309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00703.2015
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