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ERK1/2 MAPK signaling in hypothalamic paraventricular nucleus contributes to sympathetic excitation in rats with heart failure after myocardial infarction

Brain MAPK signaling pathways are activated in heart failure (HF) induced by myocardial infarction and contribute to augmented sympathetic nerve activity. We tested whether decreasing ERK1/2 (also known as p44/42 MAPK) signaling in the hypothalamic paraventricular nucleus (PVN), a forebrain source o...

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Bibliografske podrobnosti
izdano v:Am J Physiol Heart Circ Physiol
Main Authors: Yu, Yang, Wei, Shun-Guang, Zhang, Zhi-Hua, Weiss, Robert M., Felder, Robert B.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865063/
https://ncbi.nlm.nih.gov/pubmed/26801309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00703.2015
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