EP(3) receptors mediate PGE(2)-induced hypothalamic paraventricular nucleus excitation and sympathetic activation

Prostaglandin E(2) (PGE(2)), an important mediator of the inflammatory response, acts centrally to elicit sympathetic excitation. PGE(2) acts on at least four E-class prostanoid (EP) receptors known as EP(1), EP(2), EP(3), and EP(4). Since PGE(2) production within the brain is ubiquitous, the differ...

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Autores principales: Zhang, Zhi-Hua, Yu, Yang, Wei, Shun-Guang, Nakamura, Yoshiko, Nakamura, Kazuhiro, Felder, Robert B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
Materias:
Cardiovascular Neurohormonal Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197370/
https://ncbi.nlm.nih.gov/pubmed/21803943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00262.2011
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