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Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure

We previously reported that endoplasmic reticulum (ER) stress is induced in the subfornical organ (SFO) and the hypothalamic paraventricular nucleus (PVN) of heart failure (HF) rats and is reduced by inhibition of mitogen-activated protein kinase (MAPK) signaling. The present study further examined...

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Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Wei, Shun-Guang, Yu, Yang, Weiss, Robert M., Felder, Robert B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114465/
https://ncbi.nlm.nih.gov/pubmed/27496879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00362.2016
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