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Mesenchymal Stromal Cell-derived Extracellular Vesicles Promote Myeloid-biased Multipotent Hematopoietic Progenitor Expansion via Toll-Like Receptor Engagement

Mesenchymal stromal cells (MSCs) present in the bone marrow microenvironment secrete cytokines and angiogenic factors that support the maintenance and regenerative expansion of hematopoietic stem and progenitor cells (HSPCs). Here, we tested the hypothesis that extracellular vesicles (EVs) released...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Goloviznina, Natalya A., Verghese, Santhosh Chakkaramakkil, Yoon, Young me, Taratula, Oleh, Marks, Daniel L., Kurre, Peter
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114412/
https://ncbi.nlm.nih.gov/pubmed/27758863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745653
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