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Effect of 22q11.2 deletion on bleeding and transfusion utilization in children with congenital heart disease undergoing cardiac surgery

BACKGROUND: Post-surgical bleeding causes significant morbidity and mortality in children undergoing surgery for congenital heart defects (CHD). 22q11.2 deletion syndrome (DS) is the second most common genetic risk factor for CHD. The deleted segment of chromosome 22q11.2 encompasses the gene encodi...

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Detalhes bibliográficos
Publicado no:Pediatr Res
Main Authors: Brenner, Michelle K., Clarke, Shanelle, Mahnke, Donna K., Simpson, Pippa, Bercovitz, Rachel S., Tomita-Mitchell, Aoy, Mitchell, Michael E., Newman, Debra K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114022/
https://ncbi.nlm.nih.gov/pubmed/26492284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2015.216
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