Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase

Leukotrienes (LTs) are inflammatory mediators that play a pivotal role in many diseases like asthma bronchiale, atherosclerosis and in various types of cancer. The key enzyme for generation of LTs is the 5-lipoxygenase (5-LO). Here, we present a novel putative protein isoform of human 5-LO that lack...

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Udgivet i:PLoS One
Main Authors: Häfner, Ann-Kathrin, Beilstein, Kim, Graab, Philipp, Ball, Ann-Katrin, Saul, Meike J., Hofmann, Bettina, Steinhilber, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113960/
https://ncbi.nlm.nih.gov/pubmed/27855198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166591
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