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In vitro prion-like behaviour of TDP-43 in ALS
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (MND), and > 95% of familial and sporadic cases involve the deposition of insoluble aggregated, phosphorylated and cleaved TDP-43 protein. Accumulating clinical and biological evidence now indicates that ALS bears...
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| Publicado en: | Neurobiol Dis |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Academic Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5113659/ https://ncbi.nlm.nih.gov/pubmed/27590623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.08.007 |
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