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Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II
BACKGROUND: Lapachol is a natural naphthoquinone compound that possesses extensive biological activities. The aim of this study is to investigate the inhibitory effects of lapachol on rat C6 glioma both in vitro and in vivo, as well as the potential mechanisms. METHODS: The antitumor effect of lapac...
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| Veröffentlicht in: | J Exp Clin Cancer Res |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5112657/ https://ncbi.nlm.nih.gov/pubmed/27852319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0455-3 |
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