Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms

BACKGROUND: It is known that local tissue injuries incurred by snakebites are quickly instilled causing extensive, irreversible, tissue destruction that may include loss of limb function or even amputation. Such injuries are not completely neutralized by the available antivenins, which in general ar...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Strauch, Marcelo A., Tomaz, Marcelo Amorim, Monteiro-Machado, Marcos, Cons, Bruno Lemos, Patrão-Neto, Fernando Chagas, Teixeira-Cruz, Jhonatha da Mota, Tavares-Henriques, Matheus da Silva, Nogueira-Souza, Pâmella Dourila, Gomes, Sara L. S., Costa, Paulo R. R., Schaeffer, Edgar, da Silva, Alcides J. M., Melo, Paulo A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349327/
https://ncbi.nlm.nih.gov/pubmed/30689661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211229
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