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ESR1 and PGR polymorphisms are associated with estrogen and progesterone receptor expression in breast tumors

Hormone receptor-positive (HR+) breast cancers express the estrogen (ERα) and/or progesterone (PgR) receptors. Inherited single nucleotide polymorphisms (SNPs) in ESR1, the gene encoding ERα, have been reported to predict tamoxifen effectiveness. We hypothesized that these associations could be attr...

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Hertz, Daniel L., Henry, N. Lynn, Kidwell, Kelley M., Thomas, Dafydd, Goddard, Audrey, Azzouz, Faouzi, Speth, Kelly, Li, Lang, Banerjee, Mousumi, Thibert, Jacklyn N., Kleer, Celina G., Stearns, Vered, Hayes, Daniel F., Skaar, Todd C., Rae, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111879/
https://ncbi.nlm.nih.gov/pubmed/27542969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00065.2016
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