DNA Hypermethylation of ESR1 and PGR in Breast Cancer: Pathologic and Epidemiologic Associations

Improved understanding of the etiology of ERα-negative and PR-negative breast cancers may permit improved risk prediction. In vitro studies implicate DNA hypermethylation of the ERα and PR promoters in the pathogenesis of ERα-negative and PR- negative tumors, but results are not definitive. We evalu...

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Main Authors: Gaudet, Mia M., Campan, Mihaela, Figueroa, Jonine D., Yang, Xiaohong R., Lissowska, Jolanta, Peplonska, Beata, Brinton, Louise A., Rimm, David L., Laird, Peter W., Garcia-Closas, Montserrat, Sherman, Mark E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783691/
https://ncbi.nlm.nih.gov/pubmed/19861523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0678
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