Knockdown of Progesterone Receptor (PGR) in Macaque Granulosa Cells Disrupts Ovulation and Progesterone Production

Adenoviral vectors (vectors) expressing short-hairpin RNAs complementary to macaque nuclear progesterone (P) receptor PGR mRNA (shPGR) or a nontargeting scrambled control (shScram) were used to determine the role PGR plays in ovulation/luteinization in rhesus monkeys. Nonluteinized granulosa cells c...

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Vydáno v:Biol Reprod
Hlavní autoři: Bishop, Cecily V., Hennebold, Jon D., Kahl, Christoph A., Stouffer, Richard L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2016
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939739/
https://ncbi.nlm.nih.gov/pubmed/26985003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.134981
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