ESR1 and PGR polymorphisms are associated with estrogen and progesterone receptor expression in breast tumors

Hormone receptor-positive (HR+) breast cancers express the estrogen (ERα) and/or progesterone (PgR) receptors. Inherited single nucleotide polymorphisms (SNPs) in ESR1, the gene encoding ERα, have been reported to predict tamoxifen effectiveness. We hypothesized that these associations could be attr...

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Publicado en:Physiol Genomics
Main Authors: Hertz, Daniel L., Henry, N. Lynn, Kidwell, Kelley M., Thomas, Dafydd, Goddard, Audrey, Azzouz, Faouzi, Speth, Kelly, Li, Lang, Banerjee, Mousumi, Thibert, Jacklyn N., Kleer, Celina G., Stearns, Vered, Hayes, Daniel F., Skaar, Todd C., Rae, James M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
Assuntos:
Genomics of Metabolic and Tumor/Cancer Traits
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111879/
https://ncbi.nlm.nih.gov/pubmed/27542969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00065.2016
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