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DNA Targeting by a Minimal CRISPR RNA-Guided Cascade

Bacteria employ surveillance complexes guided by CRISPR (clustered, regularly interspaced, short palindromic repeats) RNAs (crRNAs) to target foreign nucleic acids for destruction. Although most type I and type III CRISPR systems require four or more distinct proteins to form multi-subunit surveilla...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Hochstrasser, Megan L., Taylor, David W., Kornfeld, Jack E., Nogales, Eva, Doudna, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111854/
https://ncbi.nlm.nih.gov/pubmed/27588603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.027
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