A Single Amino Acid Substitution Converts a Transmembrane Protein Activator of the Platelet-derived Growth Factor β Receptor into an Inhibitor

Por Petti, Lisa M., Talbert-Slagle, Kristina, Hochstrasser, Megan L., DiMaio, Daniel
Publicado em 2013

Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing

Por Klaips, Courtney L, Hochstrasser, Megan L, Langlois, Christine R, Serio, Tricia R
Publicado no eLife (2014)

Correction: Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing

Por Klaips, Courtney L, Hochstrasser, Megan L, Langlois, Christine R, Serio, Tricia R
Publicado no eLife (2015)

DNA Targeting by a Minimal CRISPR RNA-Guided Cascade

Por Hochstrasser, Megan L., Taylor, David W., Kornfeld, Jack E., Nogales, Eva, Doudna, Jennifer A.
Publicado no Mol Cell (2016)

CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference

Por Hochstrasser, Megan L., Taylor, David W., Bhat, Prashant, Guegler, Chantal K., Sternberg, Samuel H., Nogales, Eva, Doudna, Jennifer A.
Publicado em 2014