Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design

The E2 envelope glycoprotein is the primary target of human neutralizing antibody response against hepatitis C virus (HCV), and is thus a major focus of vaccine and immunotherapeutics efforts. There is emerging evidence that E2 is a highly complex, dynamic protein with residues across the protein th...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Pierce, Brian G., Keck, Zhen-Yong, Lau, Patrick, Fauvelle, Catherine, Gowthaman, Ragul, Baumert, Thomas F., Fuerst, Thomas R., Mariuzza, Roy A., Foung, Steven K. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111724/
https://ncbi.nlm.nih.gov/pubmed/27791171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614942113
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