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Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
Adoptive cell therapy (ACT) with tumor-specific T cells can mediate cancer regression. The main target of tumor-specific T cells are neoantigens arising from mutations in self-proteins. Although the majority of cancer neoantigens are unique to each patient, and therefore not broadly useful for ACT,...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7283474/ https://ncbi.nlm.nih.gov/pubmed/32518267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16755-y |
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