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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

Peptidoglycan (PGN) recognition proteins (PGRPs) are pattern-recognition receptors of the innate immune system that bind and, in some cases, hydrolyze bacterial PGNs. We determined the crystal structure, at 2.30-Å resolution, of the C-terminal PGN-binding domain of human PGRP-Iα in complex with a mu...

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Detalhes bibliográficos
Main Authors: Guan, Rongjin, Roychowdhury, Abhijit, Ember, Brian, Kumar, Sanjay, Boons, Geert-Jan, Mariuzza, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535381/
https://ncbi.nlm.nih.gov/pubmed/15572450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407856101
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