FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development

The forkhead transcription factor FoxO6 is prominently expressed during development of the murine neocortex. However, its function in cortical development is as yet unknown. We now demonstrate that cortical development is altered in FoxO6(+/−) and FoxO6(−/−) mice, showing migrating neurons halted in...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Paap, Ricardo H., Oosterbroek, Saskia, Wagemans, Cindy M. R. J., von Oerthel, Lars, Schellevis, Raymond D., Vastenhouw-van der Linden, Annemarie J. A., Groot Koerkamp, Marian J. A., Hoekman, Marco F. M., Smidt, Marten P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111667/
https://ncbi.nlm.nih.gov/pubmed/27791111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609111113
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