FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development

The forkhead transcription factor FoxO6 is prominently expressed during development of the murine neocortex. However, its function in cortical development is as yet unknown. We now demonstrate that cortical development is altered in FoxO6(+/−) and FoxO6(−/−) mice, showing migrating neurons halted in...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Paap, Ricardo H., Oosterbroek, Saskia, Wagemans, Cindy M. R. J., von Oerthel, Lars, Schellevis, Raymond D., Vastenhouw-van der Linden, Annemarie J. A., Groot Koerkamp, Marian J. A., Hoekman, Marco F. M., Smidt, Marten P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111667/
https://ncbi.nlm.nih.gov/pubmed/27791111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609111113
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