FoxO6 transcriptional activity is regulated by Thr(26) and Ser(184), independent of nucleo-cytoplasmic shuttling

Forkhead members of the ‘O’ class (FoxO) are transcription factors crucial for the regulation of metabolism, cell cycle, cell death and cell survival. FoxO factors are regulated by insulin-mediated activation of PI3K (phosphoinositide 3-kinase)–PKB (protein kinase B) signalling. Activation of PI3K–P...

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Detalhes bibliográficos
Main Authors: van der Heide, Lars P., Jacobs, Frank M. J., Burbach, J. Peter H., Hoekman, Marco F. M., Smidt, Marten P.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276963/
https://ncbi.nlm.nih.gov/pubmed/15987244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050525
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