FoxO6 transcriptional activity is regulated by Thr(26) and Ser(184), independent of nucleo-cytoplasmic shuttling

Forkhead members of the ‘O’ class (FoxO) are transcription factors crucial for the regulation of metabolism, cell cycle, cell death and cell survival. FoxO factors are regulated by insulin-mediated activation of PI3K (phosphoinositide 3-kinase)–PKB (protein kinase B) signalling. Activation of PI3K–P...

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Autori principali: van der Heide, Lars P., Jacobs, Frank M. J., Burbach, J. Peter H., Hoekman, Marco F. M., Smidt, Marten P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276963/
https://ncbi.nlm.nih.gov/pubmed/15987244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050525
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