FoxO6 transcriptional activity is regulated by Thr(26) and Ser(184), independent of nucleo-cytoplasmic shuttling

Forkhead members of the ‘O’ class (FoxO) are transcription factors crucial for the regulation of metabolism, cell cycle, cell death and cell survival. FoxO factors are regulated by insulin-mediated activation of PI3K (phosphoinositide 3-kinase)–PKB (protein kinase B) signalling. Activation of PI3K–P...

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Bibliographische Detailangaben
Hauptverfasser: van der Heide, Lars P., Jacobs, Frank M. J., Burbach, J. Peter H., Hoekman, Marco F. M., Smidt, Marten P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2005
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276963/
https://ncbi.nlm.nih.gov/pubmed/15987244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050525
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