FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development

The forkhead transcription factor FoxO6 is prominently expressed during development of the murine neocortex. However, its function in cortical development is as yet unknown. We now demonstrate that cortical development is altered in FoxO6(+/−) and FoxO6(−/−) mice, showing migrating neurons halted in...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Paap, Ricardo H., Oosterbroek, Saskia, Wagemans, Cindy M. R. J., von Oerthel, Lars, Schellevis, Raymond D., Vastenhouw-van der Linden, Annemarie J. A., Groot Koerkamp, Marian J. A., Hoekman, Marco F. M., Smidt, Marten P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111667/
https://ncbi.nlm.nih.gov/pubmed/27791111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609111113
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