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FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development

The forkhead transcription factor FoxO6 is prominently expressed during development of the murine neocortex. However, its function in cortical development is as yet unknown. We now demonstrate that cortical development is altered in FoxO6(+/−) and FoxO6(−/−) mice, showing migrating neurons halted in...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Paap, Ricardo H., Oosterbroek, Saskia, Wagemans, Cindy M. R. J., von Oerthel, Lars, Schellevis, Raymond D., Vastenhouw-van der Linden, Annemarie J. A., Groot Koerkamp, Marian J. A., Hoekman, Marco F. M., Smidt, Marten P.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111667/
https://ncbi.nlm.nih.gov/pubmed/27791111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609111113
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