Bcl-2–associated athanogene 3 protects the heart from ischemia/reperfusion injury

Bcl-2–associated athanogene 3 (BAG3) is an evolutionarily conserved protein expressed at high levels in the heart and the vasculature and in many cancers. While altered BAG3 expression has been associated with cardiac dysfunction, its role in ischemia/reperfusion (I/R) is unknown. To test the hypoth...

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Pubblicato in:JCI Insight
Autori principali: Su, Feifei, Myers, Valerie D., Knezevic, Tijana, Wang, JuFang, Gao, Erhe, Madesh, Muniswamy, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Rabinowitz, Joseph, Ramsey, Frederick V., Tilley, Douglas G., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111510/
https://ncbi.nlm.nih.gov/pubmed/27882354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90931
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