Bcl-2–associated athanogene 3 protects the heart from ischemia/reperfusion injury

Bcl-2–associated athanogene 3 (BAG3) is an evolutionarily conserved protein expressed at high levels in the heart and the vasculature and in many cancers. While altered BAG3 expression has been associated with cardiac dysfunction, its role in ischemia/reperfusion (I/R) is unknown. To test the hypoth...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Su, Feifei, Myers, Valerie D., Knezevic, Tijana, Wang, JuFang, Gao, Erhe, Madesh, Muniswamy, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Rabinowitz, Joseph, Ramsey, Frederick V., Tilley, Douglas G., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111510/
https://ncbi.nlm.nih.gov/pubmed/27882354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90931
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