Bcl-2–associated athanogene 3 protects the heart from ischemia/reperfusion injury

Bcl-2–associated athanogene 3 (BAG3) is an evolutionarily conserved protein expressed at high levels in the heart and the vasculature and in many cancers. While altered BAG3 expression has been associated with cardiac dysfunction, its role in ischemia/reperfusion (I/R) is unknown. To test the hypoth...

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發表在:JCI Insight
Main Authors: Su, Feifei, Myers, Valerie D., Knezevic, Tijana, Wang, JuFang, Gao, Erhe, Madesh, Muniswamy, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Rabinowitz, Joseph, Ramsey, Frederick V., Tilley, Douglas G., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111510/
https://ncbi.nlm.nih.gov/pubmed/27882354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90931
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