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Tetherin Antagonism by HIV-1 Group M Nef Proteins
Although Nef is the viral gene product used by most simian immunodeficiency viruses to overcome restriction by tetherin, this activity was acquired by the Vpu protein of HIV-1 group M due to the absence of sequences in human tetherin that confer susceptibility to Nef. Thus, it is widely accepted tha...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5110183/ https://ncbi.nlm.nih.gov/pubmed/27654287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01465-16 |
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