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Tetherin Antagonism by HIV-1 Group M Nef Proteins

Although Nef is the viral gene product used by most simian immunodeficiency viruses to overcome restriction by tetherin, this activity was acquired by the Vpu protein of HIV-1 group M due to the absence of sequences in human tetherin that confer susceptibility to Nef. Thus, it is widely accepted tha...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Arias, Juan F., Colomer-Lluch, Marta, von Bredow, Benjamin, Greene, Justin M., MacDonald, Julie, O'Connor, David H., Serra-Moreno, Ruth, Evans, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110183/
https://ncbi.nlm.nih.gov/pubmed/27654287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01465-16
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