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Regulation of Herpes Simplex Virus Glycoprotein-Induced Cascade of Events Governing Cell-Cell Fusion

Receptor-dependent herpes simplex virus (HSV)-induced cell-cell fusion requires glycoproteins gD, gH/gL, and gB. Our current model posits that during fusion, receptor-activated conformational changes in gD activate gH/gL, which subsequently triggers the transformation of the prefusion form of gB int...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Atanasiu, Doina, Saw, Wan Ting, Eisenberg, Roselyn J., Cohen, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110162/
https://ncbi.nlm.nih.gov/pubmed/27630245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01501-16
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