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Immune- and Nonimmune-Compartment-Specific Interferon Responses Are Critical Determinants of Herpes Simplex Virus-Induced Generalized Infections and Acute Liver Failure

The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis. Although rare, HSV-1 can also cause fulminant hepatic failure, which is ofte...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Parker, Zachary M., Pasieka, Tracy Jo, Parker, George A., Leib, David A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110161/
https://ncbi.nlm.nih.gov/pubmed/27681121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01473-16
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