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Immune- and Nonimmune-Compartment-Specific Interferon Responses Are Critical Determinants of Herpes Simplex Virus-Induced Generalized Infections and Acute Liver Failure

The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis. Although rare, HSV-1 can also cause fulminant hepatic failure, which is ofte...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Parker, Zachary M., Pasieka, Tracy Jo, Parker, George A., Leib, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110161/
https://ncbi.nlm.nih.gov/pubmed/27681121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01473-16
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