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Frontline Science: Defects in immune function in patients with sepsis are associated with PD-1 or PD-L1 expression and can be restored by antibodies targeting PD-1 or PD-L1

Sepsis is a heterogeneous syndrome comprising a highly diverse and dynamic mixture of hyperinflammatory and compensatory anti-inflammatory immune responses. This immune phenotypic diversity highlights the importance of proper patient selection for treatment with the immunomodulatory drugs that are e...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Patera, Andriani C., Drewry, Anne M., Chang, Katherine, Beiter, Evan R., Osborne, Dale, Hotchkiss, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110001/
https://ncbi.nlm.nih.gov/pubmed/27671246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4HI0616-255R
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