Frontline Science: HMGB1 induces neutrophil dysfunction in experimental sepsis and in patients who survive septic shock

Sepsis is accompanied by the initial activation of proinflammatory pathways and long-lasting immunosuppression that appears to contribute to late-occurring mortality. Although high-mobility group box 1 (HMGB1) is involved in many aspects of inflammation, its role in sepsis-induced immune suppression...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Grégoire, Murielle, Tadié, Jean-Marc, Uhel, Fabrice, Gacouin, Arnaud, Piau, Caroline, Bone, Nathaniel, Le Tulzo, Yves, Abraham, Edward, Tarte, Karin, Zmijewski, Jaroslaw W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2017
Soggetti:
Spotlight on Leading Edge Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433854/
https://ncbi.nlm.nih.gov/pubmed/27965385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.5HI0316-128RR
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