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Differential activation of RAGE by HMGB1 modulates neutrophil-associated NADPH oxidase activity and bacterial killing

The receptor for advanced glycation end products (RAGE) plays an important role in host defense against bacterial infection. In the present experiments, we investigated the mechanisms by which RAGE contributes to the ability of neutrophils to eradicate bacteria. Wild-type (RAGE(+/+)) neutrophils dem...

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Autors principals: Tadié, Jean-Marc, Bae, Hong-Beom, Banerjee, Sami, Zmijewski, Jaroslaw W., Abraham, Edward
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328912/
https://ncbi.nlm.nih.gov/pubmed/22012330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00302.2011
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