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Differential activation of RAGE by HMGB1 modulates neutrophil-associated NADPH oxidase activity and bacterial killing

The receptor for advanced glycation end products (RAGE) plays an important role in host defense against bacterial infection. In the present experiments, we investigated the mechanisms by which RAGE contributes to the ability of neutrophils to eradicate bacteria. Wild-type (RAGE(+/+)) neutrophils dem...

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Detalhes bibliográficos
Main Authors: Tadié, Jean-Marc, Bae, Hong-Beom, Banerjee, Sami, Zmijewski, Jaroslaw W., Abraham, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328912/
https://ncbi.nlm.nih.gov/pubmed/22012330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00302.2011
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