Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance

Skeletal muscle insulin resistance is a major characteristic of obesity and type 2 diabetes. Although obesity-mediated inflammation is causally associated with insulin resistance, the underlying mechanism is unclear. Here, we examined the effects of chronic obesity in mice with muscle-specific overe...

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Опубликовано в: :Mol Cell Biol
Главные авторы: Dagdeviren, Sezin, Jung, Dae Young, Lee, Eunjung, Friedline, Randall H., Noh, Hye Lim, Kim, Jong Hun, Patel, Payal R., Tsitsilianos, Nicholas, Tsitsilianos, Andrew V., Tran, Duy A., Tsougranis, George H., Kearns, Caitlyn C., Uong, Cecilia P., Kwon, Jung Yeon, Muller, Werner, Lee, Ki Won, Kim, Jason K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108883/
https://ncbi.nlm.nih.gov/pubmed/27644327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00181-16
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