Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance

Skeletal muscle insulin resistance is a major characteristic of obesity and type 2 diabetes. Although obesity-mediated inflammation is causally associated with insulin resistance, the underlying mechanism is unclear. Here, we examined the effects of chronic obesity in mice with muscle-specific overe...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Dagdeviren, Sezin, Jung, Dae Young, Lee, Eunjung, Friedline, Randall H., Noh, Hye Lim, Kim, Jong Hun, Patel, Payal R., Tsitsilianos, Nicholas, Tsitsilianos, Andrew V., Tran, Duy A., Tsougranis, George H., Kearns, Caitlyn C., Uong, Cecilia P., Kwon, Jung Yeon, Muller, Werner, Lee, Ki Won, Kim, Jason K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108883/
https://ncbi.nlm.nih.gov/pubmed/27644327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00181-16
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