Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models

Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD), is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addressed. On the other hand, disorder of gut microbiota...

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Pubblicato in:Front Physiol
Autori principali: Su, Danmei, Nie, Yuanyang, Zhu, Airu, Chen, Zishuo, Wu, Pengfei, Zhang, Li, Luo, Mei, Sun, Qun, Cai, Linbi, Lai, Yuchen, Xiao, Zhixiong, Duan, Zhongping, Zheng, Sujun, Wu, Guihui, Hu, Richard, Tsukamoto, Hidekazu, Lugea, Aurelia, Liu, Zhenqui, Pandol, Stephen J., Han, Yuan-Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108805/
https://ncbi.nlm.nih.gov/pubmed/27895587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00498
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