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Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium

BACKGROUND: Pseudomonas aeruginosa airway infections are a major cause of morbidity and mortality in patients with cystic fibrosis (CF). Azithromycin improves the related clinical outcomes, but its mechanisms of action remain poorly understood. We tested the hypothesis that azithromycin downregulate...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Leal, Teresinha, Bergamini, Gabriella, Huaux, François, Panin, Nadtha, Noel, Sabrina, Dhooghe, Barbara, Haaf, Jeremy B., Mauri, Pierluigi, Motta, Sara, Di Silvestre, Dario, Melotti, Paola, Sorio, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108761/
https://ncbi.nlm.nih.gov/pubmed/27895643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00499
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