Dysregulated Proinflammatory and Fibrogenic Phenotype of Fibroblasts in Cystic Fibrosis

Morbi-mortality in cystic fibrosis (CF) is mainly related to chronic lung infection and inflammation, uncontrolled tissue rearrangements and fibrosis, and yet the underlying mechanisms remain largely unknown. We evaluated inflammatory and fibrosis responses to bleomycin in F508del homozygous and wil...

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Autors principals: Huaux, François, Noel, Sabrina, Dhooghe, Barbara, Panin, Nadtha, Lo Re, Sandra, Lison, Dominique, Wallemacq, Pierre, Marbaix, Etienne, Scholte, Bob J., Lebecque, Patrick, Leal, Teresinha
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667188/
https://ncbi.nlm.nih.gov/pubmed/23734196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064341
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