Dysregulated Proinflammatory and Fibrogenic Phenotype of Fibroblasts in Cystic Fibrosis

Morbi-mortality in cystic fibrosis (CF) is mainly related to chronic lung infection and inflammation, uncontrolled tissue rearrangements and fibrosis, and yet the underlying mechanisms remain largely unknown. We evaluated inflammatory and fibrosis responses to bleomycin in F508del homozygous and wil...

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Detalhes bibliográficos
Main Authors: Huaux, François, Noel, Sabrina, Dhooghe, Barbara, Panin, Nadtha, Lo Re, Sandra, Lison, Dominique, Wallemacq, Pierre, Marbaix, Etienne, Scholte, Bob J., Lebecque, Patrick, Leal, Teresinha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667188/
https://ncbi.nlm.nih.gov/pubmed/23734196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064341
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