Dysregulated Proinflammatory and Fibrogenic Phenotype of Fibroblasts in Cystic Fibrosis

Morbi-mortality in cystic fibrosis (CF) is mainly related to chronic lung infection and inflammation, uncontrolled tissue rearrangements and fibrosis, and yet the underlying mechanisms remain largely unknown. We evaluated inflammatory and fibrosis responses to bleomycin in F508del homozygous and wil...

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Hauptverfasser: Huaux, François, Noel, Sabrina, Dhooghe, Barbara, Panin, Nadtha, Lo Re, Sandra, Lison, Dominique, Wallemacq, Pierre, Marbaix, Etienne, Scholte, Bob J., Lebecque, Patrick, Leal, Teresinha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667188/
https://ncbi.nlm.nih.gov/pubmed/23734196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064341
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